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What is glaucoma? PDF Print E-mail
Written by Administrator   
Sunday, 20 September 2015 00:00

All about glaucoma; symptoms, types and diagnosis of glaucoma

Glaucoma is a condition that leads to slow, but progressive loss of nerve fibres in the optic nerve. Many factors may increase the risk of this condition. If left untreated, this can lead to loss of peripheral vision (i.e. what can be seen at the sides of the visual field, rather than in the centre). In older people, glaucoma is one of the commonest causes of preventable blindness. If glaucoma progresses, it can affect all peripheral vision, then impair central vision, and -- very rarely -- may lead to very significant visual impairment. Treatments for glaucoma are aimed at bringing down the pressure in the eye to a level that is low enough to prevent harm to the optic nerve. Once the optic nerve is affected by glaucoma, lowering the pressure in the eye prevents further damage to the nerve. Damage already done to the optic nerve cannot be reversed. Screening for glaucoma is important from around age 40, every two years at least, unless you are in a higher risk group (eg Afro-caribbean race, or very strong family history of glaucoma).

Signs and symptoms of glaucoma

Symptoms of glaucoma are often absent in the early stages of the disease. Unfortunately, impaired vision is sometimes the first sign of glaucoma. Classically in angle closure glaucoma, symptoms and signs of glaucoma may include eye pain, cloudy vision, red eyes, headaches, and nausea.

How Is Glaucoma Diagnosed?

Frequent eye examinations are the best way to detect glaucoma. Your ophthalmologist will test the eye’s drainage angle, evaluate the optic nerve (ophthalmoscopy), measure eye pressure, and test the visual field of each eye (perimetry). The information from these examinations is compared at regular intervals to determine if glaucoma damage has progressed over time. Regular examinations play a critical role in the early detection of glaucoma.

Glaucoma Progression

Glaucoma typically initially affects side (peripheral) vision first. If left untreated, vision loss will continue, eventually resulting in total blindness. If glaucoma is identified early and treated appropriately, good eyesight can most likely be maintained.

Types of glaucoma.

There are several types of glaucoma, all of which affect the optic nerve. Open-angle glaucoma, the commonest form of the disease, develops when the angle between the cornea and the iris where fluid is supposed to drain from the eye is open, but the fluid drains out too slowly. Closed or narrow angle glaucoma occurs when the drainage angle is blocked by part of the iris and fluid cannot drain from the eye. Normal-tension glaucoma occurs in patients with normal intraocular pressure and is treated in the same way as open-angle glaucoma. Congenital glaucoma occurs when a child is born with a poor drainage outflow facility.

Treatment for glaucoma.

There are two main types of treatment for glaucoma: medication and surgery. Both of these treatments for glaucoma manage the disease by lowering the intraocular pressure. Medications and eye drops are common treatments, but there is the possibility of side effects, and they may eventually become ineffective over time. If the IOP cannot be managed by medications or eye drops alone, surgery or laser may be recommended. Your ophthalmologist will decide on your "target IOP" to help plan your treatment.

Recovery after Glaucoma Treatment

Glaucoma surgery is usually painless, although some patients may experience a slight stinging sensation following the procedure. Local anaesthetics are used to minimise any patient discomfort. After surgical treatments for glaucoma, it is possible to experience blurred vision or irritation. Typically, however, these effects are short-lived and normal activities, such as going to work or running errands, can be resumed after 2-3 days. This time period can be variable, it depends on the exact procedure performed.

optic disc

Last Updated on Sunday, 20 September 2015 10:11
 
Glucosamine and glaucoma PDF Print E-mail
Written by Administrator   
Friday, 11 October 2013 08:53

Taking glucosamine supplements is linked to significant, but reversible increases in intraocular pressure (IOP) in a very small, retrospective study published in JAMA Ophthalmology online. The investigators were not able to exclude the potential for long lasting damage. To put into context the potential scale and possible implications of these issues, the US prevalence of osteoarthritis is around 27 million, and glaucoma exceeds 2 million.

In this small study, only 17 patients were studied (mean age 76 years) who had a history of glucosamine supplementation and ocular hypertension (IOP > 21 mm Hg) or diagnosed open-angle glaucoma, a desire to discontinue glucosamine, 3 or more IOP measurements within 2 years, and no associated changes in glaucoma medications or eye surgery. The study was limited with its small size and design, but small significant increases in eye pressure were noted with glusoamine use - the rise in eye pressure was about 3mmHg. Clearly further studies are required to establish this association more definitively. 

"Many questions are raised by glucosamine supplementation–associated IOP changes," the study authors write. "This study shows a reversible effect of those changes, which is reassuring. However, the possibility that permanent damage can result from prolonged use of glucosamine supplementation is not eliminated."

Glucosamine is a precursor to glycosaminoglycans, and deposits of glycosaminoglycans may be deposited in the trabecular meshwork (the area of the eye where fluid drains out); there are infact other hypotheses as to how glucosamine might affect eye pressure: possibly glycosaminoglycans might have an "osmotic effect", in effect increasing fluid production inside the eye.

Given the uncertainly that now surrounds glucosamine, it would wise for glaucoma patients to discuss the issue at their eye consultations, to evaluate forthcoming literature. The current study does by its small size carry serious limitations in generaliising its applicability to the population at large at present.

JAMA Ophthalmol. Published May 23, 2013.

glucosamine and glaucoma

chondroitin and glaucoma

Chondroitin (wiki commons) is often supplemented with glucosamine and the effect of these components is not known.

Last Updated on Friday, 11 October 2013 09:45
 
iCare tonometer instructions PDF Print E-mail
Written by Administrator   
Wednesday, 09 October 2013 07:48

iCare Tonometer Instructions

Turning the tonometer on and loading the probe


1. Press the measurement button once. An LED indicator button lights up for 2 seconds to show battery voltage.

2. Once the LED is blinking, you may load the probe: remove the probe tube cap, and insert the probe into the iCare. The probe should gently drop into place. Do not push the probe into the iCare, because the probe is delicate and easily damaged. It is also possible to damage the iCare if the probe is inserted improperly. Take care with this step.

3. Press the measurement button once. This is the larger button on the top of the device.

4. The tonometer is now ready for use.

iCare instructions

Photo from iCare Quick Guide
www.icaretonometer.com

iCare instructions

Photo from iCare Quick Guide
www.icaretonometer.com

Measurement of eye pressure with the iCare tonometer

1. To alternate between normal and automatic measurements, press the mode switch with a pin until you hear a beep. This is usually "admin use only"!
2. During measurement, you will need to look straight ahead only, at a specific point, to be sure that your eye is still.
3. Bring the tonometer towards your eye. Look in a mirror (a handheld mirror, e.g. 5X magnification is fine) to check alignment. The tip of the probe needs to take its measurement from the VERY CENTRE of the cornea.
4. The probe tip should be 4 to 8 mm from the cornea. This can be tricky to set up yourself, and is the reason for the review in clinic initially, to be sure that this is correct.
5. Press the measuring button gently. Remember, keep the iCare machine steady while you press the button. Practise this with your hand held up well away from your eye before trying for the first time.
6. Six measurements are taken. A longer beep is sounded once all measurements are collected, and then the average is displayed on the machine, with the IOP range given.

The tonometer turns itself lf off automatically after one minute of inactivity.

Last Updated on Wednesday, 09 October 2013 08:52
 
World Glaucoma Week PDF Print E-mail
Written by Administrator   
Monday, 07 October 2013 08:06

World Glaucoma Week

March 6–12, 2016

www.wgweek.net


- What can you do in World Glaucoma Week? Ask a relative you know, someone that is over 40 (glaucoma is much more common over the age of 65 infact, but can develop at any age), and ask them if they have heard of glaucoma, and if not, explain that there is a test at their local optometrist that can pick it up and identify the condition early, helping to prevent sight loss.

World Glaucoma Week


Last Updated on Sunday, 20 September 2015 10:24
 
New agents for treating glaucoma: Latanoprostene bunod PDF Print E-mail
Written by Administrator   
Friday, 04 October 2013 10:53

Latanoprostene bunod is a novel compound containing a PG analogue and Nitric Oxide. It appears to offer about 1mmHg further lowering of IOP versus latanoprost, and is a well tolerated medication in early studies; data has been presented at ARVO in 2013. Nitrous oxide has been shown to relax the ciliary muscle and trabecular meshwork, possibly therefore having a combined method of action with enhanced trabecular outflow, and also increased uveoscleral outflow.

Therefore, at this stage, this new medication is likely judged to offer a small but significant advance in treatment, and its release hopefully in the next year or two is anticipated with optimism.

Bunod image

Glaucoma Medications

Last Updated on Monday, 07 October 2013 23:31
 
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