You're here : Home Glaucoma Glaucoma New glaucoma drugs have reduced need for surgery
article thumbnailMr PH Galloway, MBBS, FRCOphth

Mr Galloway is a Consultant Ophthalmic Surgeon at St James University Hospital, Leeds. His major interests are glaucoma management, and...
+ more info

article thumbnailMinimally invasive glaucoma surgery (Xen implant)

Simpler techniques for glaucoma surgery hold increasing promise for patients at risk of progressive disease. These newer micro-invasive...
+ more info

Other Articles
New glaucoma drugs have reduced need for surgery PDF Print E-mail
Written by Administrator   
Saturday, 06 August 2011 14:08

Several new classes of eye drugs over the last few years have had a dramatic effect on eye pressure control, reducing the need for surgery. The four classes of drugs used include:

1. Prostaglandins (increases fluid draining out of the eye)

2. Carbonic anhydrase inhibitors (works by reducing aqueous secretion "turning off the tap")

3. Beta blockers (works by reducing aqueous secretion "turning off the tap")

4. Alpha blockers (dual mechanism of action)

More recently, a new class of glaucoma drug has been developed. These are known as Rho kinase, or ROCK inhibitors. ROCK inhibitors have been shown to increase aqueous outflow by relaxing cells
in the trabecular meshwork and increasing the spaces between them. There also may be some "neuroprotective" benefit. Other drug classes on the horizon include an adenosine-1 agonists. Interestingly some of these drugs may be available as subtenons inserts, meaning that the drops do not need to be instilled but can be implanted just inside the lid / around the eye.

new glaucoma drugs

Last Updated on Monday, 21 September 2015 20:28